Moderna’s encouraging vaccine trial: What we know and why the biggest hurdles are still ahead

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The Phase I trail showed encouraging results, but that’s still a long way from a working vaccine that everyone can take. Biotech company Moderna reported positive Phase 1 COVID-19 vaccine trial results this morning, boosting its stock shares by 25% and drumming up a media cyclone of excitement. What does this actually mean, though? Not as much as you hope. Read Full Story

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Moderna is testing a COVID-19 vaccine on humans. This is what they’re not telling you

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Moderna reported positive Phase I testing results for its COVID-19 vaccine and will begin Phase III testing it on 30,000 humans in two weeks. News! Moderna reported positive Phase I testing results for its COVID-19 vaccine and will begin Phase III testing it on 30,000 humans in two weeks. (Separate Phase II trials are underway.) “No matter how you slice this, this is good news,” Dr. Anthony Fauci, our national bearer of bad news, told the Associated Press. Read Full Story

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COVID-19 vaccine trials are being undermined by a lack of diversity

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To make sure a vaccine works for everyone, everyone needs to be in the trials. At least 10 COVID-19 vaccines are currently in the final phase of their trials, where the vaccine is given to thousands of people to test its safety and efficacy. But as the quest for a coronavirus vaccine continues, experts say there’s still an issue with how diverse these trials are, which could impact how effective a vaccine is for everyone. Read Full Story

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Bill Gates says he’s ‘not optimistic’ COVID-19 vaccines will successfully complete trials before end of the year

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“There’s no case where we get much below the current death rate, which is about 500 deaths a day, but there’s a significant risk we go back up to the even 2,000 a day.” COVID-19 vaccine trials are well under way, but Bill Gates is not optimistic that phase III of these trials, which measures the efficacy and safety of a vaccine in a wide group of users, will be successful before the end of the year. Read Full Story

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What happens if the COVID-19 vaccines fail their trials?

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Initial tests have been promising, but what happens if none of the trials pans out? The race for a COVID-19 vaccine is unprecedented: 198 potential vaccines are now in development, and that development is happening faster than it ever has in history. Moderna, for example, finalized its vaccine just days after Chinese researchers released the genetic sequence of the new coronavirus in January. Two months later, the first volunteer was dosed with the vaccine. Last week, the company published positive Phase I trial results showing that the vaccine seems safe and generates an immune response; days later, Oxford University researchers published similarly promising results. Read Full Story

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